101 Best United States Cryptocurrency Startups – The Future of Crypto

December 26, 2021

This article showcases our top picks for the best United States based Cryptocurrency companies. These startups and companies are taking a variety of approaches to innovating the Cryptocurrency industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact
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Top United States Cryptocurrency Startups

Data sourced from Crunchbase and SemRush.

Marqeta

Marqeta

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Marqeta is a card issuing platform that provides infrastructure and tools to help companies build and manage payment programs.

Republic

Republic

Crunchbase Website Twitter Facebook Linkedin

Republic is an investment platform providing access to startups, real estate, crypto, and video game investments.

Republic

Solana

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Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

Republic

MoonPay

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MoonPay is a financial technology company that builds payments infrastructure for crypto.

Republic

Gate.io

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Gate.io is a Crypto exchange platform.

Republic

Gemini

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Gemini is a licensed digital asset exchange and custodian built for both individuals and institutions.

Republic

NYDIG

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NYDIG is a bitcoin company that provides technology and financial services to businesses in a broad range of industries.

Republic

Coinbase Ventures

Crunchbase Website Twitter Facebook Linkedin

Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

Republic

BlockFi

Crunchbase Website Twitter Facebook Linkedin

BlockFi develops a blockchain-driven wealth management platform for crypto investors.

Republic

Voyager

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Voyager is a crypto asset broker that provides retail and institutional investors with a turnkey solution.

Republic

Ripple

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Ripple provides one frictionless experience to send money globally using the power of blockchain.

Republic

Fireblocks

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Fireblocks is a blockchain security service provider for moving, storing, and issuing digital assets.

Republic

TRM Labs

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TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

Republic

Chainalysis

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Chainalysis provides blockchain data and analysis to governments, banks, and businesses worldwide.

Republic

The Sandbox

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The Sandbox develops a decentralized gaming platform that leverages non-fungible tokens and blockchain technology.

Republic

Blockchain Capital

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Blockchain Capital is a venture capital firm investing in Blockchain-enabled technology companies.

Republic

Helium

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Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

Republic

Robinhood

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Robinhood is a stock brokerage that allows customers to buy and sell stocks, options, ETFs, and cryptocurrencies with zero commission.

Republic

CoinList

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CoinList is a platform that helps blue-chip crypto projects connect with new token holders.

Republic

Bakkt

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Bakkt is a trusted digital asset platform that enables its customers to buy, sell, spend, send, and redeem digital assets.

Republic

Blockdaemon

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Blockdaemon is a blockchain deployment facilitator that manages nodes and payment rails for blockchain networks.

Republic

Circle

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Circle is a global internet finance company built on blockchain technology and powered by crypto assets.

Republic

Securitize

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Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

Republic

Public.com

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Public is an investing platform that empowers members to build a diverse portfolio of stocks, ETFs, and crypto.

Republic

Ava Labs

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AVA is a next-generation blockchain platform with revolutionary scalability, decentralization, security, and flexibility.

Republic

Iron Fish

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Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

Republic

Stacked

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Stacked is a smart automated crypto investing platform.

Republic

RTFKT

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RTFKT is a developer of custom sneakers designed for video game enthusiasts.

Republic

Roll

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Roll is building blockchain infrastructure for social money on Ethereum.

Republic

FalconX

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FalconX is a blockchain, cryptocurrency, and fintech-focused cryptocurrency brokerage and digital asset trading platform.

Republic

Wyre

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Wyre develops a wide variety of payment APIs that offer a fast and cost-effective way of transferring money.

Republic

Abra

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Abra is a digital wallet that makes it easy to access, manage, and earn interest on cryptocurrencies.

Republic

Messari

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Messari is a cryptocurrency analytics company that provides market intelligence platform for the crypto industry.

Republic

Cross River Bank

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Cross River is a financial institution that offers technology and banking services to consumers and businesses.

Republic

MobileCoin

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MobileCoin is a cryptocurrency platform that provides anti-fraud services and payment systems for merchants.

Republic

BetDEX

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BetDEX is the decentralized sports betting protocol.

Republic

Dogecoin

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Dogecoin is a peer-to-peer digital currency based on the popular doge meme founded by IBM engineers.

Republic

Chia Network

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Chia Network is building a blockchain platform based on Proofs of Space and Time.

Republic

dYdX

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dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

Republic

Zero Hash

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B2B Digital Assets-as-a-Service Technology

Republic

Bitwise

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Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Republic

Compound

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Compound is an open-source interest rate protocol that unlocks new financial applications.

Republic

BitGo

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BitGo is the leader in institutional digital asset financial services, providing clients with security, custody, and liquidity solutions.

Republic

Paradigm

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Paradigm automates OTC trading within chat for institutional traders

Republic

OpenSea

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OpenSea is a peer-to-peer marketplace for crypto collectibles and non-fungible tokens.

Republic

Sweet

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Sweet is a blockchain-based social loyalty platform that aims to improve fan engagement.

Republic

TaxBit

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TaxBit is a cryptocurrency tax and accounting software that automates tax calculations and reporting on cryptocurrency transactions.

Republic

Eco

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Eco isn’t a bank. It’s something better — a digital wallet that rewards you every time you save, spend or send money.

Republic

Gitcoin

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Gitcoin is a platform that enables open source developers to monetize their work when it is used.

Republic

Lolli

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Lolli is a rewards app that allows users to earn bitcoin when shopping online.

Republic

Solidus Labs

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Solidus Labs is a crypto-tracking company that provides tailored compliance and risk monitoring solutions for digital assets.

Republic

Flexa

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The fastest, most fraud-proof payments network in the world.

Republic

Airfox

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Airfox provides the financially underserved in emerging markets digital access to financial services.

Republic

Portal

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Portal is a financial services company that trades crypto without putting coins at risk.

Republic

Uphold

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Uphold’s technology enables individuals and businesses to invest, exchange, spend and transfer currencies, commodities, equities, and more.

Republic

NuCypher

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NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

Republic

Faraway

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Faraway makes hyper-social blockchain games with player-driven economies.

Republic

TeraWulf

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TeraWulf promises a new paradigm for crypto mining in the future, producing domestic bitcoin using over 90% zero-carbon energy.

Republic

Floating Point Group

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Floating Point Group is drastically simplifying the operations for investors to deploy cryptocurrency strategies at meaningful scale.

Republic

0x

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0x is an open protocol that enables peer-to-peer trading of assets.

Republic

Yellow Card

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Yellow Card is the easiest and most convenient way to buy and sell Bitcoin and other cryptocurrencies—no bank account required.

Republic

Coinme

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Coinme is a digital currency exchange on a mission to be the worlds trusted gateway to digital currencies and a better financial future.

Republic

CoinTracker

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CoinTracker is a portfolio and tax manager for cryptocurrency.

Republic

Aleo

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Aleo develops a platform that enables absolute privacy on Blockchains.

Republic

Dibbs

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Dibbs is a trade and collects in the only real-time, 24-7 fractional card market.

Republic

Spruce

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Spruce offers the most secure and convenient developer tools to share authentic data.

Republic

Notabene

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Notabene helps businesses perform crypto transactions that are regulatory compliant.

Republic

Harmony

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Harmony is a secure blockchain aimed to scale trust and create a radically fair economy.

Republic

Bitski

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Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

Republic

Syndicate

Crunchbase Website Twitter Facebook Linkedin

Syndicate is a decentralized asset management platform and social network.

Republic

SIMBA Chain

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Simba Chain is a cloud-based SCaaS platform that enables users to implement decentralized applications dapps for blockchain.

Republic

PolySign

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PolySign develops secure and scalable infrastructure for financial institutions to fully leverage their digital assets.

Republic

SFOX

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SFOX is a cryptocurrency prime dealer for professional traders and institutional investors.

Republic

Unlock

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Unlock is an access control protocol built on blockchain that let creators monetize their content without relying on a middleman.

Republic

Anchorage Digital

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Anchorage Digital is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

Republic

Casa

Crunchbase Website Twitter Facebook Linkedin

Casa helps consumers and companies securely store cryptocurrencies and manage private keys.

Republic

XMTP

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XMTP is a communication protocol and network that connects communities, creators, protocols, applications, and users.

Republic

Compute North

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Compute North delivers high-performance cryptocurrency mining and infrastructure solutions to customers.

Republic

Saddle Finance

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Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

Republic

Mudrex

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Mudrex is a cryptocurrency company that specializes in autopilot smart crypto investment.

Republic

MomentRanks

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MomentRanks is the premier nonfungible token (NFT) resource platform, offering analytics and tracking tools for NBA Top Shot collectors.

Republic

Set Labs

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Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

Republic

Tendermint

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Tendermint brings simplicity, security, and speed to the world’s blockchains.

Republic

Curv

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Curv is a developer of digital asset security infrastructure helping crypto-native and financial institutions to create digital wallets.

Republic

CipherTrace

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CipherTrace is a cryptocurrency intelligence company that delivers delivers cryptocurrency AML compliance solutions.

Republic

Fei Protocol

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Fei Protocol is a direct incentive stable coin which is undercollateralized and fully decentralized.

Republic

Oceidon Corporation

Crunchbase Website Twitter Facebook Linkedin

Blockchain Technology Solutions

Republic

AnChain.ai

Crunchbase Website Twitter Facebook Linkedin

AnChain.AI : Next Generation AI-powered Cryptocurrency Anti-Money Laundering

Republic

BOSONIC

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BOSONIC is a Fintech platform that eliminates counterparty credit and settlement risk in digital assets trading.

Republic

Afterparty

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Afterparty is a technology company that enables creators to directly monetize and manage NFT collector relationships.

Republic

Layer1

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Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

Republic

Talos Trading

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Talos is a technology provider of digital asset trading.

Republic

ZenSports

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Mobile sports betting against the house or peer-to-peer, using fiat or cryptocurrencies

Republic

Zerion

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Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

Republic

Algofi

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Algofi is a decentralized cryptocurrency lending platform that aims to make decentralized lending more commonly accessible.

Republic

Connext

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Connext is a crosschain liquidity network that enables fast, fully-noncustodial transfers between EVM-compatible chains and L2 systems.

Republic

Emerging Impact

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Emerging Impact modernizes financial services in emerging markets through blockchain technology.

Republic

River Financial

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River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

Republic

Stellar Development Foundation

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Stellar Development Foundation supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

Republic

Tagomi

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Tagomi is a cryptocurrency trading platform that provides access to priced liquidity, low commissions, and maximized client return.

Republic

Hummingbot

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Hummingbot is an open-source crypto trading bot that enables decentralized market making; liquidity mining for centralized exchanges.

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