101 Best California Medical Device Startups

July 31, 2021

This article showcases our top picks for the best California based Medical Device companies. California is home to Hollywood and startups that enjoy incentives to start an LLC in California. These startups and companies are taking a variety of approaches to innovating the Medical Device industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact
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Top California Medical Device Startups

Data sourced from Crunchbase and SemRush.

Imperative Care

Imperative Care

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Imperative Care is singularly dedicated to finding meaningful answers to unsolved problems in stroke.

AliveCor

AliveCor

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AliveCor is a FDA-cleared mobile heart solution that helps save lives, save money, and brings healthcare into the 21st century.

AliveCor

Cytek Biosciences

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Cytek Biosciences is a manufacturer and supplier of flow cytometry products and services.

AliveCor

Grail

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Grail develops a pan-cancer screening test designed to detect cancers at an early stage.

AliveCor

Osso VR

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Osso VR is a training and assessment platform focused on surgical virtual reality.

AliveCor

NexHealth

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NexHealth is a real-time patient booking platform for people, their doctors, and healthcare developers.

AliveCor

Dexcom

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Dexcom develops, manufactures, and distributes continuous glucose monitoring systems for diabetes management.

AliveCor

Exo

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Exo is a medical device startup which develops handheld ultrasound devices and AI for imaging and therapeutic applications.

AliveCor

Lark

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Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.

AliveCor

NeuSpera Medical

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NeuSpera, formerly known as Vivonda Medical, is developing injectable neuromodulation devices, so called “electroceuticals

AliveCor

NeuroPace

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NeuroPace develops and markets implantable devices for the treatment of neurological disorders.

AliveCor

Velano Vascular

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Velano Vascular is a medical device innovator committed to enhancing both inpatient blood collection and vascular access

AliveCor

Medable

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Medable is transforming clinical research and predictive medicine by creating a platform powered by patient generated data.

AliveCor

Eyenuk, Inc.

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Eyenuk, Inc. is a global digital health company and leader in real-world AI eye screening for autonomous disease detection

AliveCor

Viz

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Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.

AliveCor

iRhythm Technologies

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iRhythm Technologies provides diagnostic monitoring solutions that facilitate the early diagnosis and treatment of cardiac arrhythmia.

AliveCor

Premise Data

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Premise is a data and analytics platform powered by a global network of on-the-ground contributors, data science, and machine learning.

AliveCor

RayzeBio

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RayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer.

AliveCor

Synchron

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Synchron is a bioelectronics medicine company that develops neuromodulation solutions for previously-untreatable nervous system conditions.

AliveCor

PROCEPT BioRobotics

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PROCEPT BioRobotics is a surgical robotics company enabling better patient care by developing transformative solutions in urology.

AliveCor

Eargo

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Eargo makes direct-to-consumer hearing aids, allowing customers to access help for their hearing loss from their homes.

AliveCor

Ancora Heart

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Ancora Heart is dedicated to helping people with heart failure feel better and live longer.

AliveCor

Cue

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Cue helps users track their health at the molecular level, revealing the interplay of activity, food, and sleep.

AliveCor

SetPoint Medical

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SetPoint Medical treats patients with debilitating inflammatory diseases using proprietary implantable bioelectronic devices.

AliveCor

Eko

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Eko develops FDA approved, AI-powered heart sound and EKG sensors for heart disease monitoring.

AliveCor

ResMed

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ResMed provides medical equipment for treating, diagnosing, and managing sleep-disordered breathing and other respiratory disorders.

AliveCor

Qualio

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Qualio is a quality management system helping life sciences companies bring quality products to the market.

AliveCor

Bigfoot Biomedical

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Bigfoot Biomedical is a medical device company changing diabetes care for people with insulin-requiring diabetes.

AliveCor

VitalConnect

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VitalConnect is a wearable biosensor technology for wireless hospital and remote patient monitoring.

AliveCor

RxSight

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RxSight is a medical device company that offers an intraocular lens and cataract surgery solutions.

AliveCor

Pulse Biosciences

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Pulse Biosciences is a medical device company that engages in the research and development, and commercialization of CellFX system.

AliveCor

Acutus Medical

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Acutus Medical develops medical technologies to treat complex cardiac arrhythmia.

AliveCor

Tempo Automation

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Tempo Automation is the world’s first AI-driven Smart Factory designed for low volume, high complexity PBCA production.

AliveCor

Caption Health

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Caption Health is a medical company that uses artificial intelligence (AI) to interpret ultrasound exams.

AliveCor

RefleXion Medical

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RefleXion Medical is a developer of biologically-guided radiotherapy systems for patients with cancer.

AliveCor

Auris Health

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Auris Health engages in the development of robotics technology for medical applications.

AliveCor

Arterys

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Arterys is a medical imaging platform to deliver clinical AI products over the internet.

AliveCor

Avail Medsystems

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Avail Medsystems is a medical technology company that develops telemedicine software for the procedure room.

AliveCor

Truvian Sciences

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Truvian disrupts the blood-testing industry by developing an automated diagnostic system that provides lab-accurate results.

AliveCor

Eureka Therapeutics

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Eureka Therapeutics is a biotechnology company focusing on immunotherapies for the treatment of cancer.

AliveCor

ReShape Lifesciences

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ReShape Lifesciencesis a developer of minimally invasive medical devices to treat obesity and metabolic diseases.

AliveCor

Silk Road Medical

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Silk Road Medical provides research and development services of medical devices for neurovascular diseases.

AliveCor

Earlens Corporation

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Earlens is a privately held medical technology company transforming the hearing experience with the only direct sound delivery system.

AliveCor

Whisper

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Whisper develops AI-enabled, updateable hearing aids for people with hearing loss.

AliveCor

Ceribell

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Ceribell focuses on making electroencephalography (EEG) widely accessible, more efficient, and more cost-effective.

AliveCor

TRACON Pharmaceuticals

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TRACON Pharmaceuticals is a biopharmaceutical company focused on developing targeted therapies for cancer and macular degeneration.

AliveCor

Curative

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Curative is a leader in on-demand public health programs and infrastructure. Building a healthier tomorrow, together.

AliveCor

RapidAI

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RapidAI empowers clinicians to make faster, more accurate diagnostic and treatment decisions for stroke and aneurysm patients.

AliveCor

Outset Medical

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Outset Medical is a pioneering medical technology company that manufactures medical equipment.

AliveCor

Inari Medical

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Inari Medical is a medical device company that develops devices for the interventional treatment of cardiovascular diseases.

AliveCor

Enlitic

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Enlitic builds AI deep learning products to streamline radiologists’ workflows and improve healthcare diagnosis.

AliveCor

Second Sight

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Second Sight manufactures and markets implantable visual prosthetics to enable blind individuals to achieve greater independence.

AliveCor

NovaSignal

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NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system.

AliveCor

ChemoCentryx

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ChemoCentryx develops orally administered small molecule therapeutics that target chemokine receptors and related chemo-attractants.

AliveCor

Tandem Diabetes Care

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Tandem Diabetes Care develops medical devices for the treatment of diabetes offering diabetic insulin pumps for adults and children.

AliveCor

Vaxart

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Vaxart is a biotechnology company that develops vaccine technology for the treatment of infectious diseases.

AliveCor

DJO Global

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DJO Global is a manufacturer and distributor of medical devices for musculoskeletal health, vascular health, and pain management.

AliveCor

Zap Surgical Systems

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ZAP Surgical Systems designs and manufactures the ZAP-X® radiosurgery platform.

AliveCor

Neuro42

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Neuro42 is developing and commercializing advanced MRI technology for diagnosis and image-guided interventions.

AliveCor

ClearPoint Neuro

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ClearPoint Neuro is a platform neuro company that enables therapy for neuro disorders with pinpoint accuracy.

AliveCor

Pulmonx

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Pulmonx provides minimally-invasive medical devices and technologies for the diagnosis and treatment of pulmonary disorders.

AliveCor

Intarcia Therapeutics

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Intarcia Therapeutics develops therapies for diseases that require long-term chronic treatment.

AliveCor

Minerva Surgical

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Minerva Surgical is a medical device start-up company developing medical devices for women’s healthcare.

AliveCor

Promaxo

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Promaxo is commercializing customer-centric MRI systems and robotic guidance tools for live diagnosis and treatment in a physician’s office.

AliveCor

Dascena

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Dascena develops machine learning algorithms to enable early disease intervention and improve care outcomes for patients.

AliveCor

Unchained Labs

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Unchained Labs is a developer of life science biologics tools designed to help researchers break free from tools that just don’t cut it.

AliveCor

Fluxergy

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Fluxergy is a biotechnology company that offers point-of-care testing, PCR, and medical diagnostics.

AliveCor

Alphatec Spine

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Alphatec Spine is a medical device company developing products and treatments for spine disorders.

AliveCor

Shockwave Medical

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Shockwave Medical is developing the Lithoplasty™ family of balloon dilatation catheters that incorporate tiny lithotripsy electrodes.

AliveCor

Mira

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The first FDA and CE registered comprehensive women’s health and chronic disease monitoring platform with 99% of accuracy

AliveCor

Catalyst Biosciences

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Catalyst Biosciences is a drug R&D company creating catalytic biopharmaceutical products based on engineered human proteases.

AliveCor

Onera Health

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Onera Health is a world-leading research center for nano electronics and digital technology company.

AliveCor

Profusa

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PROFUSA is a medical devices company creating tissue-integrated sensors for chronic disease management and healthy living.

AliveCor

iHealth Labs

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iHealth offers cloud-based, personal healthcare products for individuals of all ages to take a more active role in managing their health.

AliveCor

InTouch Health

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InTouch Health is the leader in Acute Care Telemedicine solutions.

AliveCor

DiCE Molecules

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DiCE Molecules is a developer of transformative platform for the discovery of novel small molecules.

AliveCor

Element Science

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Element Science is a medical device and digital health start-up that develops lifesaving wearable solutions.

AliveCor

Intuity Medical

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Intuity Medical develops blood glucose monitoring systems for diabetes management.

AliveCor

Potrero Medical

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Potrero Medical is a predictive health company that is developing the next generation of smart sensors and artificial intelligence.

AliveCor

HydraFacial

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HydraFacial is an FDA registered manufacturer of advanced aesthetic technologies and products.

AliveCor

HALO Diagnostics

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HALO Diagnostics is a rapid growth technology company that creates life-changing patient insights and outcomes in radiology.

AliveCor

Evolve Biosystems

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Evolve Biosystems specializes in providing microbiome-based products designed to develop, restore, and maintain.

AliveCor

Sitka

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Sitka is a customizable video software platform that connects primary care providers to the virtual specialty provider network.

AliveCor

Dynavax Technologies

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Dynavax Technologies is a biopharmaceutical company discovering and developing novel products to prevent and treat infectious diseases.

AliveCor

Ensurge Micropower

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Solid-state microbatteries for wearables and connected sensors

AliveCor

INBRACE

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Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE.

AliveCor

Tioga Medical

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Tioga Medical is a healthcare company.

AliveCor

Biolinq

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Biolinq develops a wearable biosensor platform that is capable of measuring blood level information.

AliveCor

Halo Neuroscience

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Halo Neuroscience is a neurotech company focused on using electrical neurostimulation to unlock human performance and treat human disease

AliveCor

VoxelCloud

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VoxelCloud provides automated medical image analysis services and diagnosis assistance based on AI and cloud computing technologies.

AliveCor

NuVasive

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NuVasive is a medical device company developing minimally disruptive surgical products and procedurally integrated solutions for the spine.

AliveCor

Hound Labs

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Hound Labs is a breath technology company that has developed ultra-sensitive technology for non-invasive breath measurement.

AliveCor

Gauss Surgical

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Gauss Surgical is a med-tech company that develops a vision-based platform for accurate and real-time measurement of surgical blood loss.

AliveCor

Q’Apel Medical

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Q’Apel Medical designs access device technology for neurovascular interventions and unmet clinical needs.

AliveCor

Axonics Modulation Technologies

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Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.

AliveCor

Alveo Technologies

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Alveo is a pre-clinical stage medical diagnostics company .

AliveCor

Echo

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Echo is a provider of an automated microscope intended for biological research and pathologies.

AliveCor

Demetrix

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Demetrix is a biotechnology company that manufactures natural medicines using synthesis biology to make medical drugs.

AliveCor

EndoGastric Solutions

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EGS manufactures EsophyX technology is used to reconstruct the gastroesophageal valve in the TIF 2.0 procedure.

AliveCor

Avita Medical

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Avita is a medical company that specializes in regenerative medicine, chronic wounds, and plastic surgery.

AliveCor

ROAM

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ROAM is a San Francisco-based robotics company that is developing mobility through is powered orthotics, known as exoskeletons.

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