101 Quality Life Science Startups To Look Out For In 2021

January 24, 2021
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This article showcases Startup Pill’s top picks for the best Life Science startups. These startups are taking a variety of approaches to innovating inside of the Life Science industry and around the world. They are all exceptional startups well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Life Science Startups

Data sourced from Crunchbase and SemRush.

Scorpion Therapeutics

Scorpion Therapeutics

Crunchbase | Website | Twitter | Facebook | Linkedin

Scorpion Therapeutics was founded to broaden the reach and impact of precision medicine to more people with cancer. The company is integrating cutting-edge technologies across target discovery, medicinal chemistry, and translational medicine to deliver Precision Oncology 2.0.

Scorpion’s experienced leadership team is executing a fit-to-purpose model to efficiently unlock the next generation of precision oncology.. .

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Taysha Gene Therapies

Taysha Gene Therapies

Crunchbase | Website | Twitter | Facebook | Linkedin

Taysha Gene Therapies is a developer of treatments to eradicate severe & life-threatening monogenic diseases of the central nervous system. Taysha Gene Therapies is on a mission to eradicate monogenic CNS disease.

With a singular focus on developing curative medicines, we are able to rapidly translate our treatments from bench to bedside. We have combined our team’s proven experience in gene therapy drug development and commercialization with the world-class UT Southwestern Gene Therapy Program to quickly and efficiently build an extensive, AAV gene therapy pipeline focused on both rare and large-market indications..

Resilience

Resilience

Crunchbase | Website | Twitter | Facebook | Linkedin

Resilience provides end-to-end biopharmaceutical manufacturing and development solutions. The company is dedicated to broadening access to complex medicines and protecting biopharmaceutical supply chains against disruption.

It was founded in La Jolla, California in 2020.. .

Sherlock Biosciences

Sherlock Biosciences

Crunchbase | Website | Twitter | Facebook | Linkedin

Sherlock Biosciences is an engineering biology company offering unparalleled breadth and versatility for diagnostic solutions. It leverages engineering biology tools, including CRISPR and Synthetic Biology, to create molecular diagnostics that can rapidly deliver accurate results for a vast range of needs in virtually any setting.

They combine the diagnostic power of SHERLOCK with that of a second core platform technology, Internal Splint-Pairing Expression Cassette Translation Reaction, or INSPECTRTM, to create diagnostic tools that are simple and easy to use in virtually any setting, and at the same time provide accurate, rapid and affordable results. SheSherlock Biosciences was founded in 2019 and is headquartered in Cambridge, Massachusetts, United States..

New Amsterdam Pharma

New Amsterdam Pharma

Crunchbase | Website | Twitter | Facebook | Linkedin

New Amsterdam is a clinical-stage company focused on the research and development of transformative therapies for cardio-metabolic diseases.

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Kriya Therapeutics

Kriya Therapeutics

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Kriya is a next-generation gene therapy company focused on designing and developing transformative new treatments for highly prevalent and severe chronic diseases. We target conditions where the underlying biology is well-understood, rationally designing one-time gene therapies to durably express therapeutic proteins within the appropriate human tissues.

Our team has deep expertise in the field and includes former senior leadership from pioneering gene therapy companies and academic institutions. We use algorithmic tools, scalable infrastructure, and proprietary technology to optimize the efficacy and durability of our gene therapies – with a goal of transforming the treatment paradigm for some of the most serious and widespread diseases..

Sonoma BioTherapeutics

Sonoma BioTherapeutics

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Sonoma Biotherapeutics is a company invloved the development of adoptive Treg therapies cell for autoimmune and degenerative diseases. Using next generation genome editing and target-specific cell therapy, Sonoma is focused on developing its best-in-class platform across the entire spectrum of Treg cell therapeutic capabilities.

Founded by pioneers in Treg biology and cell therapy, the company brings together leading expertise and proprietary methodologies for the discovery and development of disease modifying and curative therapies.. .

Elevation Oncology

Elevation Oncology

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Elevation Oncology is a clinical-stage biopharmaceutical company focused on the development of precision medicines for patients.

The Protein Brewery

The Protein Brewery

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The Protein Brewery is a high-tech company that specializes in developing and making animal-free- based protein in a sustainable way. It’s a spin-out from BioscienZ and is commercializing innovative protein production using fermentation.

It was founded by Wim de Laat in 2019 and is based in Breda, Noord-Brabant, The Netherlands.. .

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Federation Bio

Federation Bio

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Federation Bio is pioneering new platforms that target diseases in which the human microbiome can play a curative role. The company’s microbial therapy leverages naturally occurring or engineered bacteria along with a diverse community of supportive bacteria to drive engraftment and durable therapeutic responses.

This approach has potential in a wide range of human conditions, from metabolic disorders and cholestatic diseases to cancer and autoimmune conditions.. .

Artiva Biotherapeutics

Artiva Biotherapeutics

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Artiva Biotherapeutics is a private biotech company advancing a pipeline of off-the-shelf, allogeneic NK cell therapies, for the treatment of hematologic cancers or solid tumors. Artiva Biotherapeutics was founded on the understanding that NK cells hold enormous therapeutic potential as cancer therapies and the dedication and expertise to overcome technological barriers in the scaling and manufacturing of these cells.

At Artiva, our mission is to deliver highly effective cell therapies that are also safe and immediately available and accessible to any cancer patient who stands to benefit. Artiva’s platform delivers scalability, quality, and cryopreservation to support a pipeline of safe, effective, versatile, and accessible product candidates..

Aulos Bioscience

Aulos Bioscience

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Aulos Bioscience is dedicated to revolutionizing patient care in cancer with highly differentiated immuno-oncology therapeutics.

PetDx

PetDx

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PetDx operates as a molecular diagnostics company dedicated to revolutionizing the detection and ultimately treatment of cancer for pets.

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Aerovate Therapeutics

Aerovate Therapeutics

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Aerovate Therapeutics is a biotechnology company focused on developing drugs that meaningfully improve the lives of patients with rare cardiopulmonary disease. Aerovate’s program is a potentially disease-modifying drug, AV-101, for people who suffer from pulmonary arterial hypertension (PAH).

AV-101 is a proprietary inhaled dry powder formulation of the drug imatinib that delivers this medicine directly to diseased lung tissues while reducing systemic adverse side effects. The company was founded and incubated by RA Capital Management, a multi-stage investment manager focused on healthcare and life sciences..

Dren Bio

Dren Bio

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Dren Bio focuses on protein engineering technologies for depletion of cells, protein aggregates, and other disease-causing agents.

Affinia Therapeutics

Affinia Therapeutics

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Affinia Therapeutics is a biotechnology company that focuses on developing transformative gene therapies for devastating diseases.

Celevity

Celevity

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Celevity is a seed-stage company that develops drugs to help dogs live longer, healthier lives. It sees aging as a disease that is able to be slowed and improved with medicines.

It was spun out of Laura Deming’s The Longevity Fund. Celevity is headquartered in San Francisco, California..

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Ventus Therapeutics

Ventus Therapeutics

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Ventus Therapeutics is a biopharmaceutical company discovering and developing novel small molecule medicines that target the innate immune system to treat autoimmune diseases, inflammatory diseases and cancer. Our structural immunology platform offers unprecedented insight into mechanisms and molecular structures, combining core capabilities for precisely targeting the innate immune system: proprietary protein engineering capabilities that elucidate innate immune mechanisms, and leading-edge rational and structure-based drug design tools.

Ventus has built an emerging pipeline of multiple drug programs addressing key targets in the innate immune system.. .

Myeloid Therapeutics

Myeloid Therapeutics

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Myeloid Therapeutics is an immunology company focused on combining immunologic insights with cutting-edge technologies to harness myeloid cells to eradicate cancer and other diseases. The Company’s ATAKTM platform technology can be broadly applied, and it is initially advancing a cell therapy program for T cell lymphoma and a primed monocyte approach to treat glioblastoma.

The ATAK platform is scalable to multiple treatment modalities and other disease areas in collaboration with partners.. .

GentiBio

GentiBio

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GentiBio is a biotherapeutics company developing engineered regulatory T cells (EngTregs) programmed to treat autoimmune allergic diseases. The early-stage biotherapeutics company co-founded by pioneers in Treg biology and synthetic immunology to develop engineered regulatory T cells (EngTregs) programmed to treat autoimmune, alloimmune, autoinflammatory, and allergic diseases.

GentiBio’s proprietary autologous and allogeneic EngTregs platform integrates key complementary technologies needed to successfully restore immune tolerance and overcome major limitations in existing regulatory T-cell therapeutics. GentiBio is at the forefront of leveraging a unique therapeutic modality that can be used to address the fundamental cause of many diseases that result from overshooting and/or malfunctioning of the immune system.

GentiBio is a Seattle, Washington-headquartered company launched in 2020 by Adel Nada, Chandra Patel, and Andy Walker.. .

FerGene

FerGene

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FerGene is an new Gene therapy, spin off Ferring Pharmaceuticals.

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ExeVir Bio

ExeVir Bio

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ExeVir Bio is a Belgium-based company that develops single-domain antibody-based therapies that help patients ward off viral infections. The company is harnessing a llama-derived antibody technology platform to generate robust antiviral therapies providing broad protection against coronaviruses.

They using a highly innovative and clinically validated VHH technology to develop treatments for viral infections that may pose a significant global threat. ExeVir Bio develops a rapid response platform for antivirals.

This platform technology enables an agile response to new health threats thanks to its short throughput time to generate drug candidates. The resulting protein-based therapeutics are sufficiently stable and easy to produce at a reasonable cost to enable true global access.

ExeVir Bio was founded in 2020 and is headquartered in Zwijnaarde, Belgium.. .

Immunitas Therapeutics

Immunitas Therapeutics

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Immunitas is unlocking human immunology using novel single cell analyses to develop targeted therapeutics for patients with challenging, complex cancers. Translating findings from laboratory research to meaningful clinical advances in humans is a longstanding challenge in the oncology field.

Immunitas was founded to directly address this problem and unlock a variety of novel drug targets based on discovery rooted in human biology. They are pursuing this goal with a team of pioneers in these areas across their scientific founders, management, and investors.

At Immunitas, they employ a single cell sequencing platform to dissect the biology of immune cells in human tumors. Their focus on human samples allows us to start with and stay closer to the most relevant and translatable biology for patients and accelerates the pace of their research.

They are identifying novel, exciting oncology targets and, importantly, developing key biomarkers to guide the selection of patients who may benefit from their new drugs. They are leveraging expertise in antibody discovery and engineering to create powerful therapies that modulate these targets, and are currently advancing a number of programs toward early human studies..

Base Genomics

Base Genomics

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Base Genomics is an epigenetics company based on TAPS (TET-assisted pyridine borane sequencing), a new invention to sequence DNA methylation developed at the Ludwig Institute for Cancer Research Branch at the University of Oxford. TAPS is a novel chemical reaction that converts methylated cytosine to thymine under mild conditions.

Unlike bisulfite sequencing, TAPS does not degrade DNA, meaning that more DNA is available for sequencing. It also retains sequence complexity, cutting sequencing costs and enabling simultaneous epigenetic and genetic analysis..

Walden Biosciences

Walden Biosciences

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Walden Biosciences is a biotechnology company focused on transforming the treatment of kidney disease.

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Neuroglee Therapeutics

Neuroglee Therapeutics

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Neuroglee Therapeutics is a digital therapeutic platform created to treat patients in the early stages of the disease.

Engrail Therapeutics

Engrail Therapeutics

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Engrail is forging a new direction to reduce the enormous burden of diseases that impact the nervous system. We unite biological insights with clinically meaningful solutions to build and catalyze a diversified portfolio of transformative medicines.

Harnessing our rigorous scientific approach to identify the most promising therapies, we leverage our flexible transaction model to advance assets with validated mechanisms and efficiently move them through development to commercialization.. .

JADBio

JADBio

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Make your life easier, automate the machine learning process. JADBio automatically searches for the best algorithms, runs the preprocessing, selects the right features, tunes for hyper-parameters, and produces the final model and predictive performance, with lots of visualizations, graphs, and reports.

JADBio can credibly process small sample sizes and large feature sets, or produce multiple feature subsets that lead to equally predictive models for knowledge discovery.. .

Civetta Therapeutics

Civetta Therapeutics

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Civetta Therapeutics is a cancer therapeutics company to advance new medicines through small molecule targeting of beta-propeller domains. The company leverages small molecule targeting of beta-propeller domains to develop important therapeutics for cancers and other diseases.

It also develops a broad range of expertise in drugging the propeller domains, spanning from biochemistry to biology to medicinal chemistry Propeller proteins are structural scaffolds that mediate protein-protein interactions of unique substrates. These proteins are found ubiquitously across cell types and can have diverse functional roles in the pathogenesis of cancer, neurodegeneration, metabolic disease, and other areas.

Their vision is to build a portfolio of therapeutics by integrating a broad range of expertise in drugging the propeller domains spanning from biochemistry to biology to medicinal chemistry. These efforts will support the creation of near term therapeutics and longer-term value in becoming a leader in this space.

Civetta Therapeutics was founded in 2019 and is based in Cambridge, Massachusetts, United States.. .

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Ona Therapeutics

Ona Therapeutics

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Ona Therapeutics is focused on the discovery and development of therapeutic biologics to treat metastatic cancer.

TissueLabs

TissueLabs

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The platform for creating organs and tissues in the lab.They are building a new platform to create organs and tissues in the lab. By combining tissue-specific extracellular matrix proteins as self-assembling hydrogels, they offer the most advanced microenvironment for cell and tissue culture.

Their products are created to allow you to perform state of the art research, from drug discovery to organ fabrication.. .

Evommune

Evommune

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Evommune is taking a tissue-based approach to advance insights and accelerate the development of transformative medicines.

CoviCept Therapeutics

CoviCept Therapeutics

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CoviCept Therapeutics is focused on the development of a small molecule that inhibits the replication and spread of RNA viruses.

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Xilis

Xilis

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Xilis is an oncology and precision health company that diagnosed cancer and find the right treatment. The company uses “micro-organoids” to make thousands of 3D replicas of a patient’s tumor in about six days, which the company says can be used for testing for drug compatibility faster.

It was founded in 2019 and is headquartered in Chapel Hill, North Carolina.. .

Known Medicine

Known Medicine

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Known Medicine primarily engages in ensuring to provide the right treatment for every patient by combining biology research & AI techniques.

Enviral Tech

Enviral Tech

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Enviral Tech is a biotechnology company that focuses on environmental viral building surveillance solutions. Its patented COVID surface testing and COVID air testing provide early coronavirus detection for the health of communities, by preventing new infections and improving business and consumer confidence.

Founded in March 2020, Enviral Tech has processed upwards of 20,000 coronavirus surface tests in more than 100 facilities nationwide.. .

Lycia Therapeutics

Lycia Therapeutics

Crunchbase | Website | Twitter | Facebook | Linkedin

Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras. The company was founded by Carolyn R.

Bertozzi in 2019 and is based in San Diego, California, USA.. .

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Kingdom Supercultures

Kingdom Supercultures

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Kingdom Supercultures creates microbial cultures that help food manufacturers to create new foods with boosted benefits.

Micronoma

Micronoma

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Life Science Cancer Diagnostic company

FoRx Therapeutics

FoRx Therapeutics

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FoRx Therapeutics is a biotechnology company developing a new generation of cancer drugs focusing on novel DNA Replication Stress pathways.

Evozyne

Evozyne

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Evozyne is a biotechnology company that specializes in protein design and molecular scale. Its mission is to unlock the potential of novel proteins to solve complex human and societal challenges by revolutionizing protein design.

It was founded in 2020 and headquartered in Chicago, Ilinois.. .

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Myricx Pharma

Myricx Pharma

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Myricx Pharma is a drug discovery company focused on developing small molecule inhibitors.

Genespire

Genespire

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Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases.

Adyn

Adyn

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Adyn is a biotechnology company that focuses on designing safer birth control options.

Biomage

Biomage

Crunchbase | Website | Twitter | Facebook | Linkedin

Biomage specializes in single-cell analysis transforming the life sciences. Our goal is to apply innovative computational methods to extract valuable insight from biological data, fueling cutting-edge research across biological disciplines.

Our flagship product, the Biomage Single Cell Platform empowers researchers to take ownership of their single cell data analysis, generating deep biological insight in just a few clicks.. .

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Shoreline Biosciences

Shoreline Biosciences

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Shoreline Biosciences is a biomedical company intended to establish immunotherapies for seriously ill patients. Its proprietary cell therapy technology platform is based on deep expertise in iPSC differentiation methods and genetic programming of the IL-15/CISH pathway for enhanced metabolic fitness and persistence of the engineered NK Cells to improve anti-cancer activity.

The company was founded in 2020 and is headquartered in La Jolla, CA, USA.. .

MitoLab

MitoLab

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MitoLab is a biotechnology company building a scalable platform for mitochondrial genome engineering. It creates and sells products for use in non-clinical scientific research scenarios.

The company’s products are designed to be used in non-clinical research projects assessing the utility of chemical compounds for mitochondrial medicine. Their customers range from multinational companies to individuals specializing in mitochondrial, metabolic, and anti-aging research.

Founded by Fahim Farzadfard and Louis J. Kang in 2020 and is headquartered in Allston, Massachusetts, USA..

MiroBio

MiroBio

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MiroBio is Harnessing the natural control mechanisms of the immune system.

Holy Grail

Holy Grail

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Holy Grail builds automatic probabilistic Deep Learning for impactful research and optimization problems

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Kanaph Therapeutics

Kanaph Therapeutics

Crunchbase | Website | Twitter | Facebook | Linkedin

Kanaph Therapeutics is a biotech with activities that range from drug discovery to early-stage clinical trials. We are dedicated to developing next-generation therapeutics for oncology and autoimmune diseases.

Our oncology pipeline includes bi-specific antibodies and small molecules that have a greatly enhanced immuno-stimulatory activity in the tumor microenvironment (TME) for efficient tumor eradication. Our autoimmune disease pipeline is composed of bispecific Fc-fusions that inhibit the alternative complement pathway while inhibiting angiogenesis and downstream complement activation as well..

Switchback Systems

Switchback Systems

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Switchback Systems is an early-stage startup engaged in the rapid development of a highly scalable DNA synthesis platform. It focuses on dramatic minimization of time, cost, and waste, for utilization in a wide range of nucleic acid applications.

The company was founded in 2019 by Mary Noe.. .

Sarcura

Sarcura

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Sarcura develops a machine platform for the large scale, GMP manufacturing of personalized cell therapies. Our target is to scale global manufacturing capacity for these life saving, patient specific cancer treatments, cost effective and safe for a all patients.

We will transform existing manufacturing paradigms by using semiconductor technology to bring bioprocess control to cellular level.. .

Halodine

Halodine

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Halodine is a biopharmaceutical company focused on the development of novel antiviral therapies. Halodine is a proprietary povidone-iodine antiseptic developed by leading clinicians for repeated nasal and oral administration.

Halodine Nasal Antiseptic and Halodine Oral Rinse have been proven effective against SARS-CoV-2, the virus causing COVID-19, as well as other infections. Safe and easy-to-use, Halodine is designed to help protect hospitalized patients, health care personnel, and consumers.

It was founded and is led by practicing MDs. Founded in 2020, the company is based in Miami, Florida..

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RNAimmune

RNAimmune

Crunchbase | Website | Twitter | Facebook | Linkedin

RNAimmune is a biopharmaceutical company specializing in the discovery and development of messenger RNA (mRNA) therapeutics and vaccines. The company leverages mRNA as a data carrier to instruct the human body to produce its own proteins capable of fighting a wide range of diseases.

RNAimmune is a spin-off venture from Sirnaomics, Inc. has received a global exclusive right to the proprietary Polypeptide Lipid Nanoparticle (PLNP) technology for mRNA delivery from Sirnaomics.

The company has also developed a proprietary A.I. algorithm (ALEPVA) for antigen prediction and vaccine design.

By integrating multiple established platform technologies, the company is aiming to develop a comprehensive mRNA drug discovery and development platform, from which the company will enrich its therapeutic and vaccine product pipeline addressing tremendous unmet needs in treatments of viral infections, cancer, and rare diseases.. .

Tacalyx

Tacalyx

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Tacalyx develops therapeutics targeting cancer-specific carbohydrate antigens on the surface of metastatic malignant tumors where no satisfactory treatments exist.The name Tacalyx is derived from TACA (Tumor Associated Carbohydrate Antigen) and ‘lyx’ from the term Glycocalyx, the glycan-containing layer covering cells. Cancer cells differ from normal cells by displaying aberrant carbohydrate structures on their surfaces promoting metastasis, angiogenesis or suppression of the immune system.

TACAs result from the aberrant glycosylation that is seen with transformation to a tumor cell and represent attractive targets for cancer treatment since they are displayed with high cancer specificity and enhance tumor virulence via the mentioned diverse mechanisms.. .

BioFlyte

BioFlyte

Crunchbase | Website | Twitter | Facebook | Linkedin

BioFlyte is commercializing a revolutionary new class of fieldable aerosol mass spectrometers and complementary products for protection from biological and low-volatility chemical threats. Our instruments identify microbes including spores, vegetative bacteria, and viruses, bio-toxins, opioids, and other airborne threats to our safety and security.

Our products are designed to autonomously sample ambient air, for example, in critical infrastructure, but can also accept liquid or powder samples manually.. .

Dropprint Genomics

Dropprint Genomics

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Dropprint Genomics provides cell technology and machine learning models that characterize the immune system. It offers big data to the immune system by generating personalized maps of a patient’s immune systems to better understand, control, and improve immune health.

Jimmie Ye, Meena Subramaniam, and Rachel Gate co-founded San Francisco, California.. .

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DiogenX

DiogenX

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DiogenX is a preclinical stage biotech company, specializing in the development of pancreatic beta-cell modulators for the treatment of Type 1 (T1D) and Type 2 Diabetes (T2D). The company, which also has research labs in Nice, France, aims to discover and develop a candidate molecule that regenerates pancreatic insulin-producing cells in patients with diabetes, offering benefits in terms of quality of life and survival.

It was discovered in the laboratory of Dr. Patrick Collombat (Inserm, CNRS, Nice University) in France, DiogenX is developing an innovative therapy with the potential to be the first beta-cell regeneration drug for diabetes..

Orphion Therapeutics

Orphion Therapeutics

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Orphion Therapeutics is focused on the development of novel gene therapies for the treatment of rare and serious genetic disorders.

Cell Vault

Cell Vault

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Cell Vault offers a t-cell bank that gives healthy individuals an opportunity to jumpstart their fight against cancer. T-cells are a type of white blood cell that circulates around the body, looking for abnormalities and infections.

Specific to cancer and disease, t-cells search for and find infected or cancerous cells to kill. Sometimes, however, cancer cells are able to evade t-cells to become life-threatening conditions..

BioStrand

BioStrand

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BioStrand offers a revolutionary methodology for identifying similarities and variations in genetic data and detecting structural anchor points that will drive innovation in precision medicine, drug development and agriculture. The BioStrand methodology enables unprecedented accuracy in detecting similarities and variations in DNA, RNA and proteins.

By detecting HYFTSTM, structural 3D information is automatically integrated into the analyses, revolutionising pattern and profile detection that are critical in unraveling diseases and biological processes.. .

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eniferBio

eniferBio

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Sustainably produced protein is one of the most important aims for the future food production.

Altay Therapeutics

Altay Therapeutics

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Altay Therapeutics is a biotech company focused on finding and discovering small molecule therapies for chronic inflammatory conditions. It is currently focused on finding curative therapies for fibrosis, NASH, and liver cancer.

It develops novel small molecule drugs against transcriptional regulators that are validated drivers of disease. It was founded in 2019 and is headquartered in San Francisco, California..

Lytica Therapeutics

Lytica Therapeutics

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Lytica Therapeutics, Inc. is a biotechnology company focused on developing novel peptide therapeutics.

Pentixapharm

Pentixapharm

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Pentixapharm develop PentixaFor and PentixaTher as a theranostic radiopharmaceutical pair.

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Blue Lake Biotechnology

Blue Lake Biotechnology

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Blue Lake Biotechnology is a startup company that focuses on developing a human vaccine using a novel viral vector. Its goal is to develop PIV5-based vaccines for human disease with an initial focus on the respiratory syncytial virus, as well as obtain the FDA’s approval for phase I trial.

The company is located in Athens, Georgia and was founded in 2019 by Biao He.. .

Eikonoklastes Therapeutics

Eikonoklastes Therapeutics

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Eikonoklastes is advancing a new generation of tissue factor (TF) immunotherapies – therapeutics designed to target the cell surface receptor now known to be prevalent on key components of the tumor microenvironment. It has recently been discovered that certain pathological cells – but not healthy cells – including cancers with high unmet need and high mortality such as triple-negative breast cancer, ovarian cancer, metastatic melanoma, and a broad range of other solid tumors, express tissue factor on the surface of their cell membranes.

Several other non-cancerous indications such as endometriosis also highly and selectively express tissue factor.. .

Digzyme

Digzyme

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Digzyme is a research and development platform for creating, discovering, and evaluating new enzyme-catalyzed reactions by bioinformatics.

AVATAMED

AVATAMED

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Biotechnology, Biopharmaceutical

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Nerio Therapeutics

Nerio Therapeutics

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Nerio Therapeutics is a biotechnology company focused on the life sciences sector.

DeepUll

DeepUll

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DeepUll is a biotech company that focuses its activity on the development of a new diagnostic system for early-stage sepsis condition. DeepUll’s proposal is based on quickly identifying the pathogens and offering the antibiogram within a few hours on the one hand, and on using the data and learning about the patient’s immunological and functional status on the other.

The system allows doctors to predict the future appearance and evolution of sepsis within a short period of time and thus provide a suitable clinical response even before the symptoms arise.. .

Trident Bioscience

Trident Bioscience

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Trident Bioscience is a biotech company that stays abreast of the latest technological trends in leading protein structure.

Pera Labs

Pera Labs

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Pera Labs develops digiceuticals and AI-powered solutions for fertility.

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Gyala Therapeutics

Gyala Therapeutics

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Gyala Therapeutics is focused on developing new CAR-T therapies for treating hematological malignancies. CAR-T (chimeric antigen receptor T cells) is a type of gene therapy in which T lymphocytes -a type of white blood cells that play a key role in immune responses- are extracted from the patient and modified to attack tumour cells.

T lymphocytes are obtained through apheresis (a technique that allows separation of blood components) and genetically reprogrammed with a receptor that binds to a tumor factor. When these cells are transduced back to the patient, they are to specifically recognize tumour cells and attack them.

Several types of CAR-T cells have demonstrated efficacy in the treatment of leukemias and B cell lymphomas.. .

Lumeda

Lumeda

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Lumeda is a biotechnology company that enables practical intraoperative photodynamic therapy for treating lung cancer. The company working closely with the leading medical institutions in the field, Lumeda is developing a solution for a fast, automated intraoperative PDT procedure that offers a step improvement in treatment planning, delivery, and PDT treatment efficacy.

Lumeda is developing photonic tools that bring intelligence and control of PDT light delivery to improve its efficacy, ease of use, and treatment planning. The automated PDT light dosimetry solution enables a short, simplified intraoperative PDT (IO-PDT) procedure in NSCLC surgery with improved PDT performance, consistency, and reliability.

They applying advanced photonics instrumentation and proprietary software to automate PDT light delivery to targeted tumor and light dosimetry profiles. The company was founded in 2020 and is headquartered in Rocky Hill, CT, USA..

Finnadvance

Finnadvance

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Finnadvance has developed microfluidic devices for in-vitro microvascular network generation.

Diagtech, Inc.

Diagtech, Inc.

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Diagtech is a startup focused on healthcare innovation through R&D of medical devices and the rental of specialized medical equipment.

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Orchid BioVentures

Orchid BioVentures

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Orchid BioVentures people, capital, and technology necessary to advance novel approaches for patients with unmet needs.

Kern Systems

Kern Systems

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Kern Systems leverages the power of enzymes and software to create the world’s most scalable DNA data storage infrastructure.

Sisu Pharma

Sisu Pharma

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Sisu Pharma is dedicated to developing targeted drugs for patients with therapy-resistant Prostate Cancer. Prostate Cancer is the second most common cancer in men worldwide and there were over 1.3 million new cases of the disease globally in 2018.

There are several treatments available for Prostate Cancer but none are curative and prolonged treatment inevitably results in resistance and death. Sisu Pharma’s proprietary technology specifically targets a key protein that is critical to the survival and spread of advanced Prostate Cancer, providing desperately needed treatment for patients with no remaining options..

Cambrian Biopharma

Cambrian Biopharma

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Cambrian Biopharma is a multi-asset biotech R&D firm uniquely focused on a specific field of biomedical research: the biology of aging, also known as geroscience. We believe the future of medicine should be proactive and committed to extending our best years, not just reactive to certain diseases.

As experts in the biology of age-related disease, it is our mission to assemble the world’s best scientists to accelerate this paradigm shift. We are built on an emerging business model we call a “Distributed R&D Company” (or “DisCo”), partnering with academic geroscientists to build companies, conduct preclinical drug discovery, and manage clinical trials.

Cambrian looks to discover and develop therapeutics that target the molecular damage that arises during aging and leads to chronic disease. Our approach is to build a diverse portfolio led by scientific rigor and data, not ego.

Focusing on early-stage therapeutics, we collaborate with pioneering scientists to bring discoveries out of the lab and into the clinic as efficiently as possible. So far, we have launched 10 companies with leading geroscientists and have relationships with more than 100 geroscience-focused labs globally, translating to a toolkit for tech-transfer negotiations and rapid spinouts..

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SeromYx Systems

SeromYx Systems

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SeromYx Systems is a biotech company that provides insight into the immune function to discover and develop vaccines, immunotherapies, drugs, and diagnostics. The company was formed in July 2019 to commercialize the Systems Serology platform developed by Dr.

Galit Alter at the Ragon Institute of Harvard/MIT/MGH, with the support of DARPA and the Bill and Melinda Gates Foundation. .

Meru Biotechnologies

Meru Biotechnologies

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Meru Biotechnologies develops a compensated backscattering interferometry solution for understanding and measuring molecular binding. The Compensated Back Scattering Interferometry (CBSI) is a label-free and free solution assay technology for measuring molecular interaction.

The study of proteins often involves immobilization, labeling, fractionation, and removal from the native environment depriving them of substances needed to function properly. CBSI quantifies the interaction of molecules in solution without labeling, immobilization, tethering, or special impedance plates..

Light Bio

Light Bio

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Light Bio creates novel capabilities in bioluminescence by applying synthetic biology to the natural diversity of living light. The company participates in the bioeconomy by offering solutions for basic research, industrial processes, and consumer products.

Its current focus is on genetically encoded, self-sustainable luminescence, particularly applied to living plants. This gives scientists an opportunity to observe the inner workings in plants, and allows consumers to experience their dynamic vitality..

Neurexis

Neurexis

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Neurexis is into neuroprotective innovation for human health

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Arctic Vision

Arctic Vision

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Arctic Vision is a China-based clinical-stage specialty ophthalmology company with a leading portfolio of breakthrough technologies. The Company’s vision is to address ophthalmology’s unmet needs through innovative therapies in China, Asia, and globally.

Arctic Vision is established by top-tier life sciences investors and led by an elite team of ophthalmic industry veterans with substantial and compelling China and global experiences in R&D and commercialization of eye care products.. .

GenKnowme

GenKnowme

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GenKnowme is an innovative life science company.

OneChain Immunotherapeutics

OneChain Immunotherapeutics

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OCI develops therapies for leukaemia based on CAR–T.

ProForma Labs

ProForma Labs

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ProForma Labs is a science driven company that operates as a dynamic analytical testing lab.

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Pregenerate

Pregenerate

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We accelerate drug development and personalized medicine for arthritis using disease-on-a-chip model

Biotrends India Pvt Ltd

Biotrends India Pvt Ltd

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PASSION FOR A BETTER TOMORROW We are a green technology company committed to improving the productivity and sustainability of modern agriculture. Our range of products help farmers practice profitable agriculture by providing increased crop productivity, improved efficiency of conventional fertilizers and a reduced environmental footprint.

Our organic certified products strengthen the soil-based microbial ecosystem, stimulate crop development at key points in the growth cycle and boost natural plant resistance to pathogens and threats. With solutions for a variety of crop categories, our range of SmartGenX™ products have demonstrated its value in third-party trials in key agricultural regions worldwide.

Biotrends is now investing heavily in development of Bio Ag and Bio Pesticides and shall soon make available products suited for Seed treatment, Pre and Post-Harvest Technology, as Fungicide and Insecticide form it’s robust stable and pipeline. Biotrends has its research-based facilities in Mexico.

Our product line is based on proprietary plant-based technology (Aloe Vera) do not use any heat, reactions, and is practically Carbon Neutral, designed to support the Sustainable Intensification of Agriculture. SUSTAINABLE INTENSIFICATION OF AGRICULTURE Plant-based Input for Sustainable Agriculture It’s important that we reduce chemical footprints as we improve our Sustainable Intensification of Agriculture.

Our plant-based products further improves the sustainability and reduces all risk of cross-contamination from animal origin products or even chemical contamination. ZERO Carbon concept products including zero CO2 emission Biotrends products are manufactured through unique process of co-culture fermentation without any use of harsh chemicals or heat.

In another words, the facility is Carbon neutral production unit, there by ushering a new age Genomics and bioinformatics revolution. Probiotic Agriculture Using advances in DNA sequencing technologies, Biotrends has created a new field of research, metagenomics, allowing the comprehensive examination and selection of microbial communities to be used in Biotrends range of products for Probiotic Agricultural use..

Just Global

Just Global

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Just Global is a Technology-Based Innovative Company, with the vision to lead the research and development of products obtained experimentally in the area of agricultural biotechnology and biochemistry. It develops and markets solutions that are environmentally friendly and innovative in plant health and nutrition.

Just Global‘s vision is to look for alternative new development and production of precursors biosynthetic high added value of other methods of pest control and abuse of phytotoxic using tools such as integrated pest control, bio-stimulants of natural origin, deployment of innate or systemic immunity plant, etc.. .

Ceidos

Ceidos

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Cell therapy is based on patient cell modification to make them fight against a targeted disease once being reinjected within the patient. This is revolutionizing cancer treatment but unfortunately, extremely expensive.

The manufacturing of those “living drugs” requires precise monitoring during the whole process. Ceidos is developing a device automatizing this process and ensuring better outcomes for a much lower price, making this therapy accessible for a larger amount of patients..

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GRIP Molecular Technologies

GRIP Molecular Technologies

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GRIP Molecular is a molecular detection device used at point-of-care to enable the rapid identification of chemical and biological threats.

ND BioSciences

ND BioSciences

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ND BioSciences is developing diagnostics and therapies for neurodegenerative diseases.

Viatris

Viatris

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Viatris is a global pharmaceutical company formed in 2020 through the combination of Mylan and Upjohn, a legacy division of Pfizer.

DIG labs

DIG labs

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DIG labs is re-imagining personalized pet wellness. We believe that our pets are the family members who love us unconditionally.

The best way to love them back is by proactively caring for their health and wellness, especially because they can’t tell us what’s wrong. Our Mission: Delivering custom insights and solutions that are convenient, accessible, and continuously advancing, enabled by the power of technology and science.

We strive to give our pets a voice and create a two-way dialogue of insights +actions,so they can live healthy, beautiful lives. A female-founded, NY-based venture-backed startup, DIG labs is developing patent-pending, tech-enabled insights and personalized products, including supplements.

Founded by former CPG R&D, brand management execs and pet lovers whose vision is to translate the benefits of personalized human healthcare to our pets, DIG labs is actively launching its proprietary real-time health platform, powered by patent-pending computer vision & machine learning. The B2C platform includes a personalized supplements business, and the B2B services platform will service categories across the petcare ecosystem..

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GOURMEY

GOURMEY

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GOURMEY is France’s first cultivated meat company. Its mission is to accelerate the world’s transition toward humane, sustainable and healthy meat by harvesting it directly from animal cells.

GOURMEY is first reinventing France’s most famous delicacy: foie gras.. .

Entheon Biomedical

Entheon Biomedical

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Entheon is a addiction recovery solution that harnesses and optimizes the therapeutic potential of the DMT molecule.

EVQLV

EVQLV

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An AI-powered technology company accelerating biologic therapy discovery, design and optimization

BIMINI Biotech

BIMINI Biotech

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BIMINI Biotech is a startup that develops innovative therapeutic strategies for oncology. It is developing therapeutic strategies that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1) for oncology, metabolic diseases, and aging.

The company was founded in 2019 and is based in Leiden, The Netherlands.. .

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